L-Carnosine is a naturally occurring di-peptide composed of the bonded amino acids alanine and histidine and is found in the brain, heart, skin, muscles, kidneys and stomach. L-Carnosine is naturally produced in the body by the enzyme carnosine synthetase. L-Carnosine supports healthy aging and cellular rejuvenation by its effects on two mechanisms: Glycation and Free Radical Damage. Glycation is the oxidation of proteins by glucose resulting in cross-linking of proteins and which is implicated in loss of cell function and accelerated aging. Probably the most common aging disease is Diabetes. Diabetics have a considerable amount more cross-linking than non-diabetics. L-Carnosine also protects the aging process of the brain by retarding lipid peroxidation and stabilizing cell membranes. The exact role of carnosine is not well understood, but studies indicate that this nutrient has antioxidant potential and may also act as a neurotransmitter (chemical messenger in the nervous system). Clinical trials have shown promise in the battle against Alzheimer’s disease. In recent studies autistic children received 800 mg of carnosine a day and were compared with a group of children on placebo. After 8 weeks, children given carnosine showed statistically significant improvements on several tests including vocal and visual recognition. Carnosine is a potent free-radical scavenger. The latest research indicates that apart from the function of protecting cells from oxidation-induced stress damage - glycation, carnosine appears to be able to extend the lifespan of cultured cells. Carnosine is not only effective in prevention, but it is also active after free radicals react to form other dangerous compounds, therefore it is rare in its action of being effective before and after damage has occurred. Carnosine seems to delay the impairment of eyesight with aging, effectively preventing and treating senile cataract and other age-related diseases. Please look at the information on Can-C which contains n-alpha-acetyl-carnosine. Therefore it is a reasonable conclusion that carnosine may be applied as a drug against aging, and is especially useful for diabetics. The exact role of carnosine supplementation in human health is not clear at this time but carnosine appears to be a promising nutrient with much potential. It is said that carnosine will be as popular and well known as vitamin E in the future. In fact for optimum anti-oxidant protection carnosine is well tolerated when used in conjunction with vitamin E and CoQ10 (please see Idebenone). The usual dosage is between 50 – 300mg per day. For general anti-aging purposes less has proven to be effective and more than 300mg per day in fact begins to become ineffective. Please be aware that some companies always think more is better and rely on dubious clinical data to draw their conclusions. We have taken our information from the world’s leading expert on carnosine Dr Marios Kyriazis. Approved Uses |